Nhà máy Stada



Pack size:

Box of 1 blister x 10 vaginal tablets.



Each vaginal tablet contains metronidazole 500 mg,

nystatin 100,000 IU and neomycin sulfate 65,000 IU.



24 months from the date of manufacturing.

Store in a well-closed container, in a dry place.

Protect from light. Do not store above 30oC.


  • Indications and Dosage & Administration
  • Contraindications
  • Adverse reactions
  • Precautions

  • Treatment of vaginitis caused by sensitive pathogens and nonspecific vaginitis.
  • For vaginal administration.
  • Moisten the tablet by dipping in water 5 to 10 seconds before the put. Patients should remain lying down for 15 minutes after putting.
  • Should be treated partner, regardless of whether clinical signs.
  • Dosage:
    Vaginitis caused by sensitive pathogens and nonspecific vaginitis: Vaginal tablet 1 or 2 times/ day for 10 consecutive days, in combination with oral treatment if necessary.

Or as prescribed by physicians.


  • Hypersensitivity to any ingredient of the drug.
  • This product should not be used concurrently with disulfiram.



The adverse drug reactions are usually dose-related. The treatment with high doses and long term increases the risk of adverse drug reactions.


  • Nausea, vomiting, anorexia, abdominal discomfort, diarrhea, metallic taste.

Less common:

  • Leukopenia.


  • Agranulocytose.
  • Seizures, peripheric polyneuropathy, headache.
  • Skin effusion, rash, itch.
  • Dark urine.


Nystatin is virtually nontoxic and nonsensitizing and is well tolerated by all age groups including debilitated infants, even on prolonged administration.

Less common:

  • Urticaria, exanthema.


  • Irritation may occur after the topical use of nystatin. Stevens – Johnson syndrome.



  • Hypersensitivity reactions including dermatitis, pruritus, drug fever and anaphylaxis.

Less common:

  • Rise in serum levels of hepatic enzymes and bilirubin, blood dyscrasias, haemolytic anaemia, confusion, paraesthesia, disorientation, nystagmus, increased salivation, stomatitis.



  • Metronidazole appears to inhibit alcohol dehydrogenase, and other alcohol oxidizing enzymes. Mild disulfiram-like reactions including flushing, headaches, nausea, vomiting, abdomical cramps and sweating have been reported.
  • Metronidazole can immobilize Treponema pallidum including the false positive reaction of Nelson test.


  • Nystatin may damage latex contraceptives, and additional contraceptive precautions may be necessary during treatment.
  • Should a reaction of hypersensitivity occur the drug should be immediately withdrawn and appropriate measures taken.


  • Prolonged local use should be avoided as it may lead to skin sensitization and possible cross-sensitivity to other aminoglycosides.

Because this product contains neomycin which can cause ototoxicity or go into the blood, it should not be used during pregnancy.
Avoid using this product during lactation.
Patients should be noted that this product may cause dizziness.



Contact us

FACTORY 1: K63/1 Nguyen Thi Soc St., Xuan Thoi Dong, Hoc Mon, HCMC
Tel: +84 28 3718 2141 - Fax: +84 28 3718 2140

FACTORY 2: 40 Tu Do Avenue, VietNam-Singapore Industrial Park, Binh Duong
Tel: +84 274 376 7470 - Fax: +84 274 376 7469
Email : stada@stada.com.vn
Website: www.stada.com.vn

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